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The 2000 Chevy Silverado requires 3 quarts of rear differential fluid, also called gear oil. It's important to replace the gear fluid every 50,000 miles to maintain proper function. Neglecting this maintenance could lead to damage to the differential and noisy operation, as well as potential safety risks such as wheels locking up while driving. Getting the fluid changed usually costs between $75 and $145, depending on the service provider. If you're knowledgeable about cars, you can save money by purchasing the fluid at places like Autozone or Walmart and performing the change yourself.
The rear differential of a 2000 Chevy Silverado can hold roughly 3 quarts of fluid.